The Mind Stone The Soul Stone is already seeing plenty of play in Standard, so The Mind Stone should see some play, too
The rebalanced version costs four mana instead of three (although he gets an extra starting loyalty to compensate), and his passive merely restricts the opponent from playing spells during his controllers turn, allowing for the use of Instants and Instant-speed abilities during parts of the turn other than the Main Phases
Because of this, vampires cards have various mechanics associated with them such as Madness, life-draining abilities, and sacrifice archetypes
It's a bit broader (being able to work on defense), a bit more combo-able (triggering ETB watchers), but more manual (requiring mana to use)
If we were just looking at the cumulative upkeep, Juju Bubble would not be a bad card