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showed little to no inhibition against other USPs tested
and has at least 500-fold higher selectivity to ErbB2 than EGFR
InChi: InChI=1S/C21H24FN5O5S/c1-13(2)31-21(28)26-8-6-14(7-9-26)32-20-16-11-25-27(19(16)23-12-24-20)18-5-4-15(10-17(18)22)33(3
24-hexahydroxy-13
5-dimethyl-2
LMT-28 ycyrrhetinic acid showed little to no inhibitionLMT 28 is an orally active and the first synthetic IL 6 inhibitor that functions through direct binding to gp130. LMT 28 shows low toxicity and selectively inhibits IL 6 induced phosphorylation of STAT3, JAK2, and gp130. Product information CAS Number: 1239600 18 0 Molecular Weight: 311. 42 Formula: C17H29NO4 Chemical Name: (4S) 3 [(2S,3S) 3 hydroxy 2 methyl 4 methylidenenonanoyl] 4 (propan 2 yl) 1,3 oxazolidin 2 one Smiles:
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