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It promotes Cdc20 autoubiquitination and inhibits cyclin proteolysis in mitotic Xenopus oocyte extracts (IC50 ~ 12 μM) and blocks cyclin degradation in interphase extract
CP-640186 Catalog No.:M19365-C It promotes Cdc20 autoubiquitination andCP 640186 is a potent and cell permeable Acetyl CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Product information CAS Number: 591778 68 6 Molecular Weight: 485. 62 Formula: C30H35N3O3 Chemical Name: (3R) 1' (anthracene 9 carbonyl) 3 (morpholine 4 carbonyl) 1,4' bipiperidine Smiles: O=C(C1C2=CC=CC=C2C=C2C=CC=CC2=1)N1CCC(CC1)N1C[C@@H](CCC1)C(=O)N1CCOCC1 InChiKey:
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