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CHIR99021 is typically used at 3 µM final concentration in cell culture
Epub 2012 Jun 26
9% (w/v) saline
54(8):2592-601
2 μM for promoter activity of the MITF target gene TRPM-1
A66 - CAS# 1166227-08-2 Catalog No.:M7134-10 CHIR99021 is typically used atA66, CAS No. 1166227 08 2, is a potent and highly selective p110 inhibitor with IC50 of 32 nM in a cell free assay, >100 fold selectivity for p110 over other class I PI3K isoforms. A66 blocks phosphoinositide 3 kinase signalling and tumour growth in certain cell types. Product information CAS Number: 1166227 08 2 Molecular Weight: 393. 53 Formula: C17H23N5O2S2 Synonym: A66 A 66 A 66 Chemical Name: (S) N1 (2 (tert butyl) 4' methyl [4,5' bithiazol] 2'
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