Silver sulfadiazine Catalog No.:M28183-C Smiles: O[C@H]1[C@@H]2O[C@H]3O[C@H](CBr)[C@@H](O[C@H]4O[C@H](CBr)[C@@H](O[C@H]5O[C@H](CBr)[C@@H](O[C@H]6O[C@H](CBr)[C@@H](O[C@H]7O[C@H](CBr)[C@@H](O[C@H]8O[C@H](CBr)[C@@H](O[C@H]9O[C@H](CBr)[C@@H](O[C@@H](O[C@@H]2CBr)[C@@H]1O)[C@H](O)[C@H]9O)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O

Name: Silver sulfadiazine Catalog No.:M28183-C Smiles: O[C@H]1[C@@H]2O[C@H]3O[C@H](CBr)[C@@H](O[C@H]4O[C@H](CBr)[C@@H](O[C@H]5O[C@H](CBr)[C@@H](O[C@H]6O[C@H](CBr)[C@@H](O[C@H]7O[C@H](CBr)[C@@H](O[C@H]8O[C@H](CBr)[C@@H](O[C@H]9O[C@H](CBr)[C@@H](O[C@@H](O[C@@H]2CBr)[C@@H]1O)[C@H](O)[C@H]9O)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O
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Description

Smiles: O[C@H]1[C@@H]2O[C@H]3O[C@H](CBr)[C@@H](O[C@H]4O[C@H](CBr)[C@@H](O[C@H]5O[C@H](CBr)[C@@H](O[C@H]6O[C@H](CBr)[C@@H](O[C@H]7O[C@H](CBr)[C@@H](O[C@H]8O[C@H](CBr)[C@@H](O[C@H]9O[C@H](CBr)[C@@H](O[C@@H](O[C@@H]2CBr)[C@@H]1O)[C@H](O)[C@H]9O)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O

with 14 nM and 590 nM in FLIPR depolarized assaay and FLIPR hyperpolarized assay

TrxR inhibitor D9 (2-20 nM

CAS Number: 102-02-3

9 µM at 24 and 48 hrs

Silver sulfadiazine Catalog No.:M28183-C Smiles: O[C@H]1[C@@H]2O[C@H]3O[C@H](CBr)[C@@H](O[C@H]4O[C@H](CBr)[C@@H](O[C@H]5O[C@H](CBr)[C@@H](O[C@H]6O[C@H](CBr)[C@@H](O[C@H]7O[C@H](CBr)[C@@H](O[C@H]8O[C@H](CBr)[C@@H](O[C@H]9O[C@H](CBr)[C@@H](O[C@@H](O[C@@H]2CBr)[C@@H]1O)[C@H](O)[C@H]9O)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3OSilver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication. Product information CAS Number: 22199 08 2 Molecular Weight: 357. 14 Formula: C10H9AgN4O2S Chemical Name: silver(1+) 4

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