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Makishima M
a novel plasminogen activator inhibitor-1 inhibitor
AZ-5104 was identified to exhibit 5-fold potency compared to AZD-9291
COC1=CC2=NC=NC(NC3=CC(Cl)=C(F)C=C3)=C2C=C1OCCCN1CCOCC1
improves the pathomorphology of the injured spinal cord
Marinopyrrole A ticasone (propionate) Makishima MMarinopyrrole A (Maritoclax) is a selective Mcl 1 antagonist. It binds to Mcl 1, but not Bcl XL, and targets Mcl 1 for proteasomal degradation. Maritoclax disrupts the interaction between Bim and Mcl 1 with an IC50 of 10. 1 M. Product information CAS Number: 1227962 62 0 Molecular Weight: 510. 15 Formula: C22H12Cl4N2O4 Chemical Name: 2 [4,4',5,5' tetrachloro 2' (2 hydroxybenzoyl) 1'H [1,3' bipyrrole] 2 carbonyl]phenol Smiles:
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