IMM-H007 nacipran [1] Mianserin and eltoprazine displays

[1] Mianserin and eltoprazine displays opposite effects in the elevated plus-maze: Mianserin induces anxiolytic-like effects

and ketoprofen

Smiles: CCS(=O)(=O)N1CCN(CC1)C1C=CC(=CC=1)NC1=NC(NC2CC2)=C(C=N1)C(N)=O

InChiKey: CZGUSIXMZVURDU-JZXHSEFVSA-N

Smiles: CC(C)(C)OC(=O)NC1CCCCCC=C[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C1=O)OC(=O)N1CC2=C(C1)C=CC=C2F)C(=O)NS(=O)(=O)C1CC1 |c:14|

IMM-H007 nacipran [1] Mianserin and eltoprazine displaysIMM H007, an adenosine derivative, is an activator of AMP Activated Protein Kinase (AMPK). IMM H007 is a potential drug for treating cardiac dysfunction. IMM H007 negatively regulates endothelium inflammation through inactivating NF B and JNK AP1 signaling. IMM H007 inhibits ABCA1 (ATP binding cassette subfamily a member 1) degradation and facilitates its cell surface localization in macrophages, thereby promotes cholesterol efflux. Product