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2', 5-Difluoro-2'-deoxycytidine culine RWJ 67657 inhibits TNF-alpha production

SKU: 99443809487

4.6
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Description

RWJ 67657 inhibits TNF-alpha production in lipopolysaccharide-injected mice (87% inhibition at 50 mg/kg) and in rats (91% inhibition at 25 mg/kg) after oral administration

2', 5-Difluoro-2'-deoxycytidine culine RWJ 67657 inhibits TNF-alpha production2',5 Difluoro 2' deoxycytidine, compound 13, has potent anti HCV activity and toxicity to ribosomal RNA (rRNA). Product information CAS Number: 581772 30 7 Molecular Weight: 263. 20 Formula: C9H11F2N3O4 Chemical Name: 4 amino 5 fluoro 1 [(2R,3R,4R,5R) 3 fluoro 4 hydroxy 5 (hydroxymethyl)oxolan 2 yl] 1,2 dihydropyrimidin 2 one Smiles: NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1F InChiKey: OCMREAUZQAIMOT UAKXSSHOSA N InChi: InChI=1S C9H11F2N3O4

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