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LCL161 Size:Solid 10 mg 7 μM induces apoptosis in

SKU: 47079887051

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Description

7 μM induces apoptosis in human promyelocytic leukaemia HL-60 cells

1188890-41-6

also known as barbaloin

2-amino-N-[(2R)-1-[(3R)-3-benzyl-3-(N

A comparative study of their rates of beta-oxidation and esterification of palmitate and their sensitivity to R-etomoxir

LCL161 Size:Solid 10 mg 7 μM induces apoptosis inLCL161 is a n orally bioavailable second mitochondrial derived activator of caspases (SMAC) mimetic and inhibitor of IAP (Inhibitor of Apoptosis Protein) family of proteins, with potential antineoplastic activity. SMAC mimetic LCL161 binds to IAPs, such as X chromosome linked IAP (XIAP) and cellular IAPs 1 and 2. Since IAPs shield cancer cells from the apoptosis process, this agent may restore and promote the induction of apoptosis through apoptotic

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