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that is also capable of inhibiting various types of cancer cells by inhibiting the STAT3 activation pathway and human fibrosarcoma cells by reducing the expression of matrix metalloproteinase-9 by acting through the glucocorticoid receptor
SB-267268 11271 that is also capable ofSB 267268 is a selective and nonpeptidic alpha(v)beta3 (v3) and alpha(v)beta5 (v5) integrins antagonist, with Kis of 0. 9, 0. 5 and 0. 7 nM for human v3, monkey v3 and human v5, respectively. SB 267268 inhibits human and mouse v3 with IC50s of 0. 68 and 0. 29 nM, respectively. SB 267268 reduces angiogenesis and VEGF expression. Product information CAS Number: 205678 26 8 Molecular Weight: 451. 44 Formula: C22H24F3N3O4 Chemical Name: 2 [(4S) 3 oxo 8 {3
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