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Smiles: CC1(C)C(=O)N(C(=S)N1C1=CC(F)=C(C=C1)C(=O)NC)C1C=C(C(=CC=1)C#N)C(F)(F)F
SRI-011381 hydrochloride promotes fibrillar Aβ clearance by macrophages
PKC-iota inhibitor 1
CN1C=C(C2=C(C3=C4CC(CN)CCN4C4=CC=CC=C34)C(=O)NC2=O)C2=CC=CC=C12
PF-4136309 inhibits hERG potassium current with an IC50 of 20 μM
ABC294640 - CAS# 915385-81-8 Catalog No.:M6465-10 Smiles: CC1(C)C(=O)N(C(=S)N1C1=CC(F)=C(C=C1)C(=O)NC)C1C=C(C(=CC=1)C#N)C(F)(F)FABC294640, also known as Opaganib, CAS No. 915385 81 8, is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase 2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preventing the phosphorylation of the pro apoptotic amino alcohol sphingosine to sphingosine 1 phosphate (S1P), the lipid mediator that is pro survival and critical for
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